Covid-19: Vaccines Should Work Against Omicron Variant, WHO Says

Existing vaccines should still protect people who contract the Omicron variant from severe Covid cases, a World Health Organization (WHO) official says. It comes as the first lab tests of the new variant in South Africa suggest it can partially evade the Pfizer jab.

Researchers say there was a "very large drop" in how well the vaccine's antibodies neutralised the new strain. But the WHO's Dr Mike Ryan said there was no sign Omicron would be better at evading vaccines than other variants.

"We have highly effective vaccines that have proved effective against all the variants so far, in terms of severe disease and hospitalisation, and there's no reason to expect that it wouldn't be so" for Omicron, Dr Ryan, the WHO's emergencies director asserted.

He said initial data suggested Omicron did not make people sicker than the Delta and other strains. "If anything, the direction is towards less severity," he said. The new South African study - which has not yet been peer-reviewed - found the Pfizer/BioNTech vaccine may result in up to 40 times fewer neutralising antibodies against Omicron than against the original Covid strain.

But Omicron's ability to escape vaccine antibodies is "incomplete", said Prof Alex Sigal, a virologist at the Africa Health Research Institute, who led the research.He said the results, based on blood tests from 12 people, were "better than I expected of Omicron".



Boosters will enhance protection
Prof Sigal said vaccination, combined with the previous infection, could still neutralise against the variant. That suggests boosters may bring a significant benefit. Scientists believe the previous infection, followed by vaccination or a booster, is likely to increase the neutralisation level and will probably protect people against severe disease. More data on how well the Pfizer jab works against Omicron is expected to be released in the coming days.

UK Prime Minister Boris Johnson's spokesman said early signs suggested Omicron could be more transmissible than the current Delta strain. But Omicron's ability to cause severe disease is not yet clear. Dr Anthony Fauci, the top US infectious diseases expert, said early evidence suggests Omicron could be more transmissible but less severe.